Sharing openly to move science forward is a key value of the Moore Lab. We view Open Science as existing in two crucial dimensions, Horizontal and Vertical. Horizontal Open Science is sharing tools and information with other scientists; Vertical integration is sharing that seeks to cross educational levels. The product of both is accelerated discovery (ideas and findings that change the way we think) and innovation (new methods and findings that change the way we act).
OPEN SCIENCE
NeuroNex Technology Hub
Our NeuroNex Technology Hub is a collaboration between four labs and is supported by the National Science Foundation. We are discovering new ways to use BioLuminescence combined with OptoGenetics (BL-OG) to image and control cells and are committed to openly sharing our knowledge and tools.
In addition to distributing our tools by request or via Addgene, we share knowledge with other scientists through our website, conduct symposia and tailored workshops, and send members of our group to interested labs via our emissary program. We are also committed to education and develop a variety of in-person and online activities to train students of all levels. Posters and protocols, educational materials, and metadata for our molecular constructs are routinely archived in the Brown Digital Repository and we maintain a constructs database.
Human Neocortical Neurosolver
Led by Dr. Stephanie Jones’ group at Brown, Human Neocortical Neurosolver (HNN) is open-source software is available to researchers to explore their EEG/MEG data and make hypotheses about human brain circuits in healthy and diseased states. Read the paper in eLife and check out the HNN website.
DiscoveryEngine
The DiscoveryEngine seeks to empower scientists, by understanding the full landscape of discovery. Built on a Bayesian perspective of optimal information in science, we are having scientists rate the degree to which a paper changed their view of the topic (formally, ‘Discovery Value’) and the degree to which it could change practices (formally, ‘Innovation Value’). A key conviction of the DiscoveryEngine is that this data is best gathered openly and democratically, providing a voice for reward in science where all can participate.
Open Ephys
Open Ephys was founded by two Moore lab members, Drs. Josh Siegle and Jakob Voigts. This platform promotes the sharing of new technologies in neuroscience, including the Open Ephys electrophysiology hardware and software originally developed by Jakob and Josh, now used in over 150 labs and improved on by a large and active community.